教室研究業績(2013年〜)

◎2017

  1. 吉山裕規, 飯笹久, キムヒョジ(出願人 国立大学法人 島根大学). Epstein-Barrウイルス関連癌に特異的な抗腫瘍剤. 特願2017-160164 (2017) “New!!”
  2. Deyno S, Fekadu S, Astatkie A. Resistance of Staphylococcus aureus to antimicrobial agents in Ethiopia: a meta- analysis. Antimicrob Resist Infect Control
 6:85 (2017) doi: 10.1186/s13756 -017-0243-7.
  3. Nishikawa J, Iizasa H, Yoshiyama Y, Nakamura M, Saito M, Sasaki S, Shimokuri K, Yanagihara M, Sakai K, Suehiro Y, Suehiro Y, Yamasaki T, Sakaida I. The Role of Epigenetic Regulation in Epstein-Barr Virus-Associated Gastric Cancer. Int J Mol Sci 18 (8): E1606 (2017). doi:10.3390/ijms18081606.
  4. Kim H, Iizasa H, Kanehiro Y, Fekadu S, Yoshiyama H. Herpesviral microRNAs for cellular metabolism and immune responses. Front Microbiol 8:1318 (2017). doi: 10.3389/ fmicb. 2017.01318.
  5. 金廣優一飯笹久吉山裕規. Epstein-Barrウイルス関連がんとRNA/DNA編集酵素. 月刊 「細胞 」(ニューサイエンス社) 49 (8): p37-39 (2017).
  6. Kawaguchi Y, Nariki H, Kawamoto N, Kanehiro Y, Miyazaki S, Suzuki M, Magari M, Tokumitsu H, Kanayama N. SRSF1-3 contributes to diversification of the immunoglobulin variable region gene by promoting accumulation of AID in the nucleus. Biochem Biophys Res Commun 485 (2) : 261-266 (2017) .
  7. Torii Y, Kawada JI, Murata T, Yoshiyama H, Kimura H, Ito Y. Epstein-Barr  virus infection-induced inflammasome activation in human monocytes. PLoS One 12(4): e0175053 (2017).
  8. 金廣優一飯笹久吉山裕規. EBウイルス感染症(特集:古くて新しい日和見感染症). 臨床と微生物 (近代出版) 44 (1): p69-76 (2017).

◎2016

  1. 飯笹久. 疾患におけるA-to-I RNA編集酵素ADAR1の役割(特集:DNA/RNA編集研究の新たな眺望). Seikagaku (日本生化学会雑誌) 88:593-599 (2016).
  2. 村松正道、飯笹久. DNA/RNA編集の新たな眺望(特集:DNA/RNA編集研究の新たな眺望). Seikagaku (日本生化学会雑誌) 88:555-556 (2016).
  3. 吉山裕規金廣優一Kim HyojiMuhtar AmrizalRicardo Timmy飯笹久. 感染に伴って起こるがん: Epstein-Barrウイルス関連胃癌を中心に.  島根医学  36: 1-6 (2016).
  4. Nanbo A, Kachi K, Yoshiyama H, Ohba Y. Epstein-Barr virus exploits host endocytic machinery for cell-to-cell viral transmission rather than a virological synapse. J Gen Virol 97(11):2989-3006 (2016).
  5. 飯笹久Hyoji Kim吉山裕規. EBウイルス関連胃癌研究の最近の動向. EBウイルス関連胃癌. 診断と治療社 p32-35(2016).
  6. 金廣優一Richardo Timmy飯笹久吉山裕規. EBウイルスの胃上皮細胞への感染と不死化. EBウイルス関連胃癌. 診断と治療社 p53-59(2016).
  7. 柳井秀雄、西川潤、吉山裕規、清水則夫:編集. EBウイルス関連胃癌. 診断と治療社(2016).
  8. Murata T, Noda C, Narina Y, Watanabe T, Yoshida M, Ashio K, Sato Y, Goshima F, Kanda T, Yoshiyama H, Tsurumi T, Kimura H. Induction of Epstein-Barr virus oncoprotein latent membrane protein 1 (LMP1) by transcription factor activating protein 2 (AP-2) and early B cell factor (EBF). J Virol 90:3873-2889 (2016).
  9. Sarlak G, Htoo HH, Hernandez J-F, Rizzino A, Iizasa H, Konietzko U, Checler F, Postina R, Song W, Bruno V. Sox2 functionally interacts with beta APP, the beta APP intracellular domain and ADAM10 at a transcriptional level in human cells. Neuroscience 312 : 153-164 (2016).

◎2015

  1. Iizasa H, Ishihara S, Richardo T, Kanehiro Y, Yoshiyama H. Dysbiotic infection in the stomach. World J Gastroenterol 21 (40): 11450-11457 (2015).
  2. 飯笹久吉山裕規. 組換えEBウイルス作成法-遺伝子治療への応用-. EBウイルス 改定第3版. 診断と治療社 p198-203(2015).
  3. 高田賢蔵:監修、柳井秀雄、清水則夫、吉山裕規:編集. EBウイルス 改定第3版. 診断と治療社(2015).
  4. Kataoka S, Muramatsu H, Okuno Y, Hayashi Y, Mizoguchi Y, Tsumura M, Okada S, Kobayashi M, Sano C, Sato H, Oh-Iwa I, Ito M, Kojima D, Hama A, Takahashi Y, Kojima S. Extrapulmonary tuberculosis mimicking Mendelian susceptibility to mycobacterial disease in a patient with signal transducer and activator of transcription 1 (STAT1) gain-of-function mutation. J Allergy Clin Immunol  137(2):619-622 (2015).
  5. Tatano Y,  Kanehiro Y, Sano C, Shimizu T, Tomioka H. ATP exhibits antimicrobial action by inhibiting bacterial utilization of ferric ion. Sci Rep 5: 8610 (2015).
  6. Kanda T, Miyata M, Kano M, Kondo S, Yoshizaki T, Iizasa H. Clustered microRNAs of the Epstein-Barr Virus cooperatively downregulate an epithelial cell-specific metastasis suppressor.  J Virol 89 (5): 2684-2697 (2015).  
  7. Kohayagawa Y, Ishitobi N, Yamamori Y, Wakuri M, Sano C, Tominaga K, Ikebe T.  Streptococcal toxic shock syndrome from necrotizing soft-tissue infection of the breast caused by a mucoid type strain. J Infect Chemother 21 (2): 144-147 (2015).

◎2014

  1. Nishikawa J, Yoshiyama H, Iizasa H, Kanehiro Y, Nakamura M, Nishimura J, Saito M, Okamoto T, Sakai K, Suehiro Y, Yamasaki T, Oga A, Yanai H, Sakaida I. Epstein-Barr virus in gastric carcinoma. Cancers  6 (4): 2259-2274 (2014).
  2. Gallat FX, Matsugaki N, Coussens NP, Yagi KJ, Boudes M, Higashi T, Tsuji D, Tatano Y, Suzuki M, Suzuki M, Mizohata E, Tono K, Kameshima T, Park J, Song C, Hatsui T, Yabashi M, Nahgo E, Itoh K, Coulibaly F, Tobe S, Ramaswamy S, Stay B, Iwata S, Chavas LM. In vivo crystallography at X-ray free-electron lassers: the next generation of structural biology? Philos Trans R Soc Lond B Biol Sci 369 (1647): 20130497(2014).
  3. Tatano Y, Shimizu T, Tomioka H. Unique macrophages different from M1/M2 macrophages inhibit T cell mitogenesis while upregulating Th17 polarization. Sci Rep 4: 4146 (2014).
  4. Sai Y, Nishimura T, Muta M, Iizasa H, Miyata T, Nakashima E. Basic fibroblast growth factor is essential to maintain endothelial progenitor cell phenotype in TR-BME2 cells. Biol Pharm Bull 37 (4): 688-693 (2014).
  5. Okamoto T, Hayashi Y, Yanai H, Nishikawa J, Nakazawa T, Iizasa H, Jinushi M, Sakaida I, Yoshiyama H*. Colonization of an acid resistant Kingella denitrificans in the stomach may contribute to gastric dysbiosis by Helicobacter pylori. J Infect Chemother 20 (3): 169-174 (2014). (*Corresponding author)
  6. Takeda S, Kanbayashi D, Kurata T, Yoshiyama H, Komano J.Enhanced susceptibility of B lymphoma cells to measles virus by EBV type III latency that up-regulates CD150/SLAM. Cancer Sci 105 (2): 211-218 (2014).
  7. Thirion M, Kanda T, Murakami Y, Ochiya T, Iizasa H*. “MicroRNAs and oncogenic human viruses.”MicroRNAs: Key Regulators of Oncogenesis. (Ed. Sadegh Babashah) Springer, 155-182 (2014). (*Corresponding author)

◎2013

  1. Baghdadi M, Yoneda A, Yamashina T, Nagao H, Komohara Y, Nagai S, Akiba H, Foretz M, Yoshiyama H, Kinoshita I, Dosaka-Akita H, Takeya M, Viollet B, Yagita H, Jinushi M. TIM-4 Glycoprotein-mediated degradation of dying tumor cells by autophagy leads to reduced antigen presentation and increased immune tolerance. Immunity 39 (6): 1070-1081 (2013).
  2. Goudarzi H, Iizasa H, Furuhashi M, Nakazawa S, Nakane R, Liang S, Hida Y, Yanagihara K, Kubo T, Nakagawa K, Kobayashi, M, Irimura T, Hamada J. Enhancement of in vitro cell motility and invasiveness of human malignant pleural mesothelioma cells through the HIF-1 alpha-MUC1 pathway. Cancer Lett 339 (1): 82-92 (2013).
  3. Liang S, Furuhashi M, Nakane R, Nakazawa S, Goudarzi H, Hamada J*, Iizasa H*. Isolation and characterization of human breast cancer cells with SOX2 promoter activity. Biochem Biophys Res Commun 437 (2): 205-211 (2013)(*Corresponding author)
  4. Ota H, Sakurai M, Gupta, R, Valente L, Wulff B-E, Ariyoshi K, Iizasa H, Davuluri RV, Nishikura K. ADAR1 Forms a Complex with Dicer to Promote MicroRNA Processing and RNA-Induced Gene Silencing. Cell 153 (3): 578-589 (2013).
  5. Oda K, Nishimura T, Higuchi K, Ishido N, Ochi K, Iizasa H, Sai Y, Tomi M, Nakashima E. Estrogen Receptor alpha Induction by Mitoxantrone Increases Abcg2 Expression in Placental Trophoblast Cells. J Pharm Sci 102 (9): 3364-3372 (2013).
  6. Goudarzi H,Hida Y, Takano H, Teramae H, Iizasa H, Hamada J. Hypoxia affects in vitro growth of newly established cell lines from patients with malignant pleural mesothelioma. Biomed Res 34 (1): 13-21 (2013).
  7. Nanbo A, Kawanishi E, Yoshida R, Yoshiyama H. Exosomes derived from Epstein-Barr virus-infected cells are internalized via caveolae-dependent endocytosis and promote phenotypic modulation in the target cells. J Virol 87(18): 3420-3439 (2013).
  8. Jinushi M, Yagita H, Yoshiyama H, Tahara H. Putting the brake on anticancer therapies: negative regulation of innate immune pathways by tumor-associated myeloid cells. Trends Mol Med 19 (9): 536-545 (2013).
  9. Baghdadi M, Yoshiyama H, Akiba Hi, Yagita H, Akita H, Jinushi M. Combined blockade of TIM-3 and TIM-4 augments cancer vaccine efficacy against established melanomas. Cancer Immunol Immunothera 62(4): 629-637 (2013).
  10. Valente L, Kawahara Y, Zinshteyn B, Iizasa H, Nishikura K. Post-transcriptional gene regulation by an Editor: ADAR and its role in RNA Editing. Post-transcriptional gene regulation: RNA processing in eukaryotes. (Ed. Jane Y.Wu) Wiley-VCH Verlag GmbH, 41-82 (2013).