岡田俊平 (Shunpei Okada)

助教

栃木県出身 東京大学大学院博士課程終了 博士(工学)

[専門] RNA生物学、ウイルス学

s.okada (A) med.shimane-u.ac.jp   (A)は、アットマークへ変更

論文 

  1. Liu Y, PhyoWai A, Iida Y, Tumurgan Z, Okada S, Iizasa H, Yoshiyama H. Exploring the anti-EBV potential of suberoylanilide hydroxamic acid: leading apoptosis in infected cells by suppressing BART gene expression and inducing lytic infection. Virology.597:110161 (2024)
  2. Wadi AFAA, Onomura D, Funamori H, Khatun MM, Okada S, Iizasa H, Yoshiyama H. Effect of strain differences, humidity changes, and saliva contamination on inactivation of SARS-CoV-2 by ions. Viruses 16(4):520 (2024)
  3. Noda Y, Okada S, Suzuki T. Regulation of A-to-I RNA editing and stop codon recoding to control selenoprotein expression during skeletal myogenesis. Nat Commun. 13(1):2503 (2022).
  4. Yang Y, Okada S, Sakurai M. Adenosine-to-inosine RNA editing in neurological development and disease. RNA Biol. 18(7):999-1013 (2021).
  5. Sakurai M, Okada S, Ueda H, Yang Y. Discovering A-to-I RNA Editing Through Chemical Methodology “ICE-seq”. Methods Mol Biol. 2181:113-148 (2021).
  6. Suzuki T, Yashiro Y, Kikuchi I, Ishigami Y, Saito H, Matsuzawa I, Okada S, Mito M, Iwasaki S, Ma D, Zhao X, Asano K, Lin H, Kirino Y, Sakaguchi Y, Suzuki T. Complete chemical structures of human mitochondrial tRNAs. Nat Commun. 11(1):4269 (2020).
  7. Hojo H, Yashiro Y, Noda Y, Ogami K, Yamagishi R, Okada S, Hoshino SI, Suzuki T. The RNA-binding protein QKI-7 recruits the poly(A) polymerase GLD-2 for 3′ adenylation and selective stabilization of microRNA-122. J Biol Chem. 295(2):390-402 (2020).
  8. Okada S, Ueda H, Noda Y, Suzuki T Transcriptome-wide identification of A-to-I RNA editing sites using ICE-seq. Methods 156:66-78 (2019). 
  9. Uchida H, Matsumura S, Okada S, Suzuki T, Minami T, Ito S. RNA editing enzyme ADAR2 is a mediator of neuropathic pain after peripheral nerve injury. FASEB J. 31(5):1847-1855 (2017). 
  10. Ishida K, Miyauchi K, Kimura Y, Mito M, Okada S, Suzuki T, Nakagawa S.Regulation of gene expression via retrotransposon insertions and the noncoding RNA 4.5S RNAH. Genes Cells. 20(11):887-901 (2015).
  11. Okada S, Sakurai M, Ueda H, Suzuki T. Biochemical and Transcriptome-Wide Identification of A-to-I RNA Editing Sites by ICE-Seq. Methods Enzymol. 560:331-353 (2015).
  12. Suzuki T, Ueda H, Okada S, Sakurai M. Transcriptome-wide identification of adenosine-to-inosine editing using the ICE-seq method. Nat Protoc. 10(5):715-732 (2015).
  13. Sakurai M, Ueda H, Yano T, Okada S, Terajima H, Mitsuyama T, Toyoda A, Fujiyama A, Kawabata H, Suzuki T.A biochemical landscape of A-to-IRNA editing in the human brain transcriptome. Genome Res. 24(3):522-534 (2014).

 

研究費

文部科学省科学研究補助金

令和1年度-令和3年度 若手研究 (代表) 19K16037

「ゲノム構造Rループ形成のエピトランスクリプトミクス制御」

その他

令和4年度(2022年度)大分大学グローカル感染症研究センター共同研究 

「SARS-CoV-2  サブゲノムRNA合成機構の解明に基づく治療薬開発」